The Run Kilkee 10k follows an out-and-back route along the Loop Head Peninsula, starting and finishing in Kilkee town near the horseshoe bay. The course is set on paved roads along the Wild Atlantic Way, traveling northwest toward the sea cliffs. The terrain features a steady climb over the first few kilometers, followed by rolling elevations as participants head toward the turnaround point before returning via the same coastal path to the finish line.