The Frank Duffy 10 Mile follows a single-loop route that takes place almost entirely within the scenic and expansive Phoenix Park in Dublin. As a key event in the Dublin Race Series, the course travels along wide, tarmac avenues and through wooded areas, passing landmarks such as the Papal Cross and Chesterfield Avenue. The terrain is described as challenging but fair, featuring several steady honest drags and rolling hills that test endurance without being overly brutal. Participants enjoy a traffic-free environment and strong crowd support, especially near the finish area close to the Phoenix Monument.